By plane, the closest airport to most of the region is the Asheville Regional Airport AVL located fifteen miles southeast of Asheville. The nearest regional airport to Boone is the Tri-Cities Regional Airport TRI located between Johnson City and Bristol, Tennessee. The next nearest international airports are the Greenville-Spartanburg International Airport GSP in Greenville, South Carolina, Charlotte Douglas International Airport CLT in Charlotte, North Carolina, and McGhee Tyson Airport TYS in Knoxville, Tennessee.
By train, the closest Amtrak (http://www.amtrak.com) station to the region is in Greenville, South Carolina.
By car, two major Interstate highways cross the region: Interstate 40, which traverses east-west, and Interstate 26, which traverses north-south. The scenic Blue Ridge Parkway also runs through the region.
By bus, Greyhound (http://www.greyhound.com) has stops in Asheville and Waynesville.